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In the contest between the Indianapolis Colts and Washington Commanders on Sunday, Oct. 4 at 9:30 a.m. ET, our projection model expects the Colts to come away with the victory. Seeking predictions on the final score, spread, and point total, too? Find a complete game projection below.
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Colts vs. Commanders Game Info and TV Channel
- When: Sunday, October 4, 2026 at 9:30 a.m. ET
- Where: Tottenham Hotspur Stadium in London, England
- TV: NFL Network
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Listen to the game on Big 100
Colts vs. Commanders Odds and Betting Info
- Spread favorite: Colts (-4.5)
- Moneyline: Colts (-226), Commanders (+186)
- Total: 46.5 points
Colts vs. Commanders Prediction
- Pick ATS: Commanders (+4.5)
- Pick OU: Over (46.5)
Prediction:
Colts 29 - Commanders 26
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Colts vs. Commanders Betting Insights
- The Colts have won two games against the spread this season.
- The Commanders have covered twice in three matchups with a spread this year.
- Indianapolis has covered the spread once when favored by 4.5 points or more this season (in two opportunities).
- This season, games featuring the Colts have gone over the point total twice.
- So far this year, each Commanders games has hit the over.
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