Seahawks vs. 49ers Week 18 Predictions, Odds and Stats

When the Seattle Seahawks play the San Francisco 49ers at 8 p.m. ET on Saturday, Jan. 3, our computer model predicts the Seahawks will take home the win. Our model also projects the spead, point total, and final score, which you can check out below.

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Seahawks vs. 49ers Game Info and TV Channel

  • When: Saturday, January 3, 2026 at 8 p.m. ET
  • Where: Levi's Stadium in Santa Clara, California
  • TV: ABC/ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Listen to the game on 107.7 The Bone

Seahawks vs. 49ers Odds and Betting Info

  • Spread favorite: Seahawks (-1.5)
  • Moneyline: Seahawks (-122), 49ers (+102)
  • Total: 47.5 points

Seahawks vs. 49ers Prediction

  • Pick ATS: Seahawks (-1.5)
  • Pick OU: Over (47.5)

Prediction:

Seahawks 25 - 49ers 23

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Seahawks vs. 49ers Betting Insights

    • The Seahawks have compiled an 11-5-0 ATS record so far this year.
    • The 49ers have compiled an 11-5-0 record against the spread this season.
    • Seattle has an ATS record of 9-4 when playing as at least 1.5-point favorites this season.
    • San Francisco has covered the spread once this season (1-3 ATS) when playing as at least 1.5-point underdogs.
    • In the Seahawks' 16 games this season, the combined scoring has gone over the point total nine times.
    • So far this season, 10 out of the 49ers' 16 games with a set over/under have gone over the point total.

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