Rams vs. Cardinals Week 18 Predictions, Odds and Stats

Our computer model predicts the Los Angeles Rams will beat the Arizona Cardinals on Sunday, Jan. 4 at 4:25 p.m. ET. For a complete projection on the game at SoFi Stadium, which includes our prediction on the spread, over/under, and final score, keep scrolling.

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Rams vs. Cardinals Game Info and TV Channel

  • When: Sunday, January 4, 2026 at 4:25 p.m. ET
  • Where: SoFi Stadium in Inglewood, California
  • TV: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Listen to the game on 93.1 Jack FM

Rams vs. Cardinals Odds and Betting Info

  • Spread favorite: Rams (-8.5)
  • Moneyline: Rams (-407), Cardinals (+306)
  • Total: 46.5 points

Rams vs. Cardinals Prediction

  • Pick ATS: Rams (-8.5)
  • Pick OU: Over (46.5)

Prediction:

Rams 38 - Cardinals 12

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Rams vs. Cardinals Betting Insights

    • The Rams have covered 11 times in 16 games with a spread this season.
    • The Cardinals have covered six times in 16 chances against the spread this year.
    • Los Angeles has been favored by 8.5 points or more four times this season, and covered the spread in two of those contests.
    • Arizona has been an underdog by 8.5 points or more three times this year, and covered the spread in one of those contests.
    • The Rams and their opponent have combined to go over the point total nine out of 16 times this season.
    • Cardinals games have gone over the point total nine out of 16 times this season.

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