Michael Pittman Jr. Week 16 Preview vs. the 49ers

Michael Pittman Jr. will be up against the 22nd-ranked passing defense in the league when his Indianapolis Colts take on the San Francisco 49ers in Week 16, on Monday at 8:15 p.m. ET.

Pittman has a 725-yard season on 72 catches with seven scores so far. He has been targeted on 99 occasions, and averages 51.8 yards.

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Pittman vs. the 49ers

• Pittman vs the 49ers (since 2021): 1 GP / 105 REC YPG / 1 REC TD
• San Francisco has allowed three opposing receivers to put up 100 or more receiving yards in a game in the 2025 season.
• The 49ers have conceded a TD pass to 24 opposing players this year.
• San Francisco has given up two or more TD receptions to only one opposing player on the season.
• The pass defense of the 49ers is allowing 227.6 yards per game this year, which ranks 22nd in the league.
• The 49ers have the No. 25 defense in the NFL in passing TDs allowed, giving up 25 this season (1.8 per game).

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Pittman Receiving Insights

• Pittman, in six of 14 games, has hit the over on his receiving yards prop bet.
• Pittman has been targeted on 99 of his team's 445 passing attempts this season (22.2% target share).
• He has been targeted 99 times, averaging 7.3 yards per target (74th in NFL).
• Pittman has a touchdown catch in seven of 14 games this year, but no games with more than one.
• He has 15.9% of his team's 44 offensive touchdowns this season (seven).
• With nine red zone targets, Pittman has been on the receiving end of 14.8% of his team's 61 red zone pass attempts.

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Pittman's Recent Performance