Photo: Ronald Martinez / Getty Images Sport / Getty Images
The Los Angeles Lakers (17-6) take the court against the San Antonio Spurs (16-7) as 5.5-point favorites on Wednesday, December 10, 2025 at 10 p.m. ET on Amazon Prime Video and SportsNet LA.
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Listen to the game on News Radio 1200 WOAI
Lakers vs. Spurs Predictions for Wednesday
Our computer projection model for this matchup calls for a final score of Lakers 118, Spurs 117.
- Moneyline Pick: Lakers (-226)
- Total Pick: Under 237.5 (computer predicts 234.6 points)
- Pick ATS: Spurs (+5.5)
Recent Lakers vs. Spurs Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 11/5/2025 | Spurs | -1.5 | 227.5 | -121 | +101 | 118-116 LAL |
| 3/17/2025 | Lakers | -9.5 | 230.5 | -444 | +341 | 125-109 LAL |
| 1/13/2025 | Lakers | -4 | 221.5 | -186 | +154 | 126-102 SA |
| 11/27/2024 | Lakers | -1.5 | 227.5 | -134 | +112 | 119-101 LAL |
| 11/15/2024 | Lakers | -2.5 | 228 | -138 | +117 | 120-115 LAL |
Lakers 2025-26 Betting Trends
- Los Angeles has a 14-9-0 record against the spread this season.
- In games this season they were favored by 5.5 points or more, the Lakers have a 4-4 record against the spread.
- Los Angeles' games have hit the over in 16 out of 23 opportunities (69.6%).
- The Lakers have been favorites in 12 games this season and won 10 (83.3%) of those contests.
- Los Angeles has a record of 7-1 when it's favored by -226 or more by oddsmakers this season.
Spurs 2025-26 Betting Trends
- So far this season, San Antonio has compiled a 10-11-2 record against the spread.
- The Spurs are 2-1 against the spread when an underdog by 5.5 points or more this season.
- San Antonio's games have gone over the point total 13 out of 23 times (56.5%).
- The Spurs have gone 6-3 in games they were listed as the moneyline underdog (winning 66.7% of those games).
- San Antonio has won all two games it has played as a moneyline underdog with odds of +187 or longer.
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Lakers vs. Spurs Injury Report
Lakers
Lakers:
Maxi Kleber: Questionable (Back)
Spurs
Spurs:
Victor Wembanyama: Out (Calf),
Jordan McLaughlin: Questionable (Hamstring)
Lakers vs. Spurs Game Time and TV Channel
- Game day: Wednesday, December 10, 2025
- Game time: 10 p.m. ET
- TV channel: Amazon Prime Video and SportsNet LA
- Location: Los Angeles, California
- Arena: Crypto.com Arena
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