The Louisville Cardinals and the Toledo Rockets play in the Boca Raton Bowl on December 23, 2025.
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Louisville vs. Toledo Matchup Info
- Game date: Tuesday, December 23, 2025
- Game time: 2 p.m. ET
- Location: Boca Raton, Florida
- Venue: Flagler Credit Union Stadium
- TV channel: ESPN
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Louisville vs. Toledo Odds and Prediction
- Spread favorite: Cardinals (-9)
- Moneyline: Cardinals (-330), Rockets (+262)
- Total: 44.5 points
- Pick ATS: Toledo (+9)
- Pick OU: Over (44.5)
- Prediction: Louisville 25, Toledo 21
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Louisville vs. Toledo Betting Records and Insights
- Louisville has won four games against the spread this season, while failing to cover eight times.
- Toledo has put together a 9-3-0 record against the spread this year.
- The Cardinals have been favored by 9 points or more six times this season, and covered the spread in one of those matchups.
- The Rockets have been an underdog by 9 points or more once this season, and covered the spread.
- A total of five out of 12 Louisville games this season have hit the over.
- In 2025, six Toledo games have hit the over.