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The Duke Blue Devils (5-5) face a fellow ACC foe when they visit the North Carolina Tar Heels (4-6) on Saturday, November 22, 2025 at Kenan Stadium.
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Duke vs. North Carolina Matchup Info
- Game date: Saturday, November 22, 2025
- Game time: 3:30 p.m. ET
- Location: Chapel Hill, North Carolina
- Venue: Kenan Stadium
- TV channel: ACC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Duke vs. North Carolina Odds and Prediction
- Spread favorite: Blue Devils (-7)
- Moneyline: Blue Devils (-254), Tar Heels (+205)
- Total: 51.5 points
- Pick ATS: Duke (-7)
- Pick OU: Over (51.5)
- Prediction: Duke 31, North Carolina 21
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Duke vs. North Carolina Betting Records and Insights
- Duke has covered four times in 10 games with a spread this season.
- North Carolina has won five games against the spread this year, failing to cover five times.
- The Blue Devils have been favored by 7 points or more this season twice, and failed to cover both times.
- The Tar Heels have covered the spread twice this season (2-2 ATS) when playing as at least 7-point underdogs.
- In Duke's 10 games this season, the combined scoring has gone over the point total seven times.
- In 2025, three North Carolina games have gone over the point total.