Northwestern vs. Minnesota Football Prediction & Odds - Nov. 22

The Northwestern Wildcats (5-5) meet a fellow Big Ten opponent when they host the Minnesota Golden Gophers (6-4) on Saturday, November 22, 2025 at Wrigley Field.

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Northwestern vs. Minnesota Matchup Info

  • Game date: Saturday, November 22, 2025
  • Game time: 12 p.m. ET
  • Location: Chicago, Illinois
  • Venue: Wrigley Field
  • TV channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Northwestern vs. Minnesota Odds and Prediction

  • Spread favorite: Wildcats (-3.5)
  • Moneyline: Wildcats (-182), Golden Gophers (+151)
  • Total: 40.5 points
  • Pick ATS: Northwestern (-3.5)
  • Pick OU: Over (40.5)
  • Prediction: Northwestern 25, Minnesota 17

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Northwestern vs. Minnesota Betting Records and Insights

  • Northwestern has compiled a 6-3-1 record against the spread this season.
  • Minnesota has won just two games against the spread this season.
  • When playing as at least 3.5-point favorites this season, the Wildcats have an ATS record of 3-1.
  • The Golden Gophers have covered the spread once when an underdog by 3.5 points or more this year (in four opportunities).
  • Northwestern games have hit the over five out of 10 times this season.
  • Minnesota games have hit the over six out of 10 times this year.