Photo: Matthew Stockman / Getty Images Sport / Getty Images
The Philadelphia 76ers (7-4) will look to Tyrese Maxey (third in the league scoring 32.1 points per game) when they try to knock off Cade Cunningham (10th in the NBA with 27.5 PPG) and the Detroit Pistons (10-2) on Friday, November 14, 2025 at Little Caesars Arena. The 76ers are 4.5-point road underdogs in the matchup, which begins at 7:30 p.m. ET on FDSDET and NBCS-PH.
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Pistons vs. 76ers Predictions for Friday
Our computer projections model for this encounter calls for a final score of Pistons 119, 76ers 115.
- Moneyline Pick: Pistons (-184)
- Total Pick: Over 230.5 (computer predicts 234.3 points)
- Pick ATS: 76ers (+4.5)
Recent Pistons vs. 76ers Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 11/9/2025 | Pistons | -4.5 | 234.5 | -189 | +157 | 111-108 DET |
| 2/7/2025 | 76ers | -5.5 | 226.5 | -209 | +175 | 125-112 DET |
| 11/30/2024 | Pistons | -1.5 | 217 | -130 | +109 | 111-96 PHI |
| 10/30/2024 | 76ers | -4 | 219.5 | -180 | +150 | 105-95 DET |
Pistons 2025-26 Betting Trends
- Detroit has gone 8-4-0 ATS this season.
- The Pistons have a 4-2 record against the spread in games they were favored by 4.5 points or more this season.
- Six of Detroit's 11 games with a set total have hit the over (54.5%).
- The Pistons have entered the game as favorites eight times this season and won seven of those games.
- Detroit has been at least a -184 moneyline favorite six times this season and won all of those games.
76ers 2025-26 Betting Trends
- Philadelphia is 8-3-0 against the spread this year.
- In games this year in which they were an underdog by 4.5 points or more, the 76ers have a 3-1 record against the spread.
- Philadelphia has hit the over in seven of its 11 games with a set total (63.6%).
- The 76ers have a 3-4 record in games they were listed as the moneyline underdog (winning 42.9% of those games).
- When it has played as a moneyline underdog with odds of +153 or longer, Philadelphia has a record of 2-2 (50%).
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Pistons vs. 76ers Injury Report
Pistons
Pistons:
Jaden Ivey: Out (Knee),
Marcus Sasser: Out (Hip),
Isaiah Stewart: Questionable (Ankle),
Ausar Thompson: Out (Ankle),
Tobias Harris: Out (Ankle),
Cade Cunningham: Questionable (Hip),
Jalen Duren: Questionable (Ankle)
76ers
76ers:
Paul George: Out (Knee),
VJ Edgecombe: Questionable (Back),
Joel Embiid: Out (Knee)
Pistons vs. 76ers Game Time and TV Channel
- Game day: Friday, November 14, 2025
- Game time: 7:30 p.m. ET
- TV channel: FDSDET and NBCS-PH
- Location: Detroit, Michigan
- Arena: Little Caesars Arena
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
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