The Penn State Nittany Lions (3-6) and the Michigan State Spartans (3-6) square off on Saturday, November 15, 2025 at Spartan Stadium in a clash of Big Ten opponents.
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Penn State vs. Michigan State Matchup Info
- Game date: Saturday, November 15, 2025
- Game time: 3:30 p.m. ET
- Location: East Lansing, Michigan
- Venue: Spartan Stadium
- TV channel: CBS
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Penn State vs. Michigan State Odds and Prediction
- Spread favorite: Nittany Lions (-7)
- Moneyline: Nittany Lions (-267), Spartans (+217)
- Total: 49.5 points
- Pick ATS: Michigan State (+7)
- Pick OU: Over (49.5)
- Prediction: Penn State 29, Michigan State 25
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Penn State vs. Michigan State Betting Records and Insights
- Penn State has covered just twice in nine games with a spread this season.
- Michigan State has won five games against the spread this season, failing to cover four times.
- The Nittany Lions have been favored by 7 points or more this season five times and failed to cover in all five.
- The Spartans have covered the spread when playing as at least 7-point underdogs in four of four chances this season.
- Penn State games have hit the over seven out of nine times this season.
- Michigan State games have hit the over six out of nine times this year.