Cavaliers vs. 76ers Predictions, Odds & Stats – Nov. 5

Philadelphia 76ers v Chicago Bulls

Photo: Michael Reaves / Getty Images Sport / Getty Images

The Cleveland Cavaliers (4-3) are double-digit, 10.5-point favorites against the Philadelphia 76ers (5-2) on Wednesday, November 5, 2025 at 7 p.m. ET. The matchup airs on FDSOH and NBCS-PH.

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Cavaliers vs. 76ers Predictions for Wednesday

Our computer projections model for this game expects a final result of Cavaliers 118, 76ers 117.

  • Moneyline Pick: Cavaliers (-424)
  • Total Pick: Under 235.5 (computer predicts 234.5 points)
  • Pick ATS: 76ers (+10.5)

Recent Cavaliers vs. 76ers Matchups

Cavaliers vs 76ers (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
1/24/2025 Cavaliers -9.5 228.5 -452 +346 132-129 PHI
12/21/2024 Cavaliers -10 221.5 -442 +343 126-99 CLE
11/13/2024 Cavaliers -11 218 -610 +442 114-106 CLE

Cavaliers 2025-26 Betting Trends

  • Cleveland is 2-5-0 against the spread this season.
  • The Cavaliers have not yet covered the spread as favorites of 10.5 points or more this season (0-1).
  • Out of Cleveland's seven games with a set total, two have hit the over.
  • This season, the Cavaliers have been favored seven times and won four of those games.
  • Cleveland has played as a favorite of -424 or more once this season and won that game.

76ers 2025-26 Betting Trends

  • Philadelphia has gone 5-2-0 ATS this season.
  • Philadelphia's games have hit the over five out of seven times (71.4%).
  • The 76ers have compiled a 2-2 record in games they were listed as the moneyline underdog (winning 50% of those games).
  • Philadelphia has not yet played as a moneyline underdog of +330 or longer.

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Cavaliers vs. 76ers Injury Report

Cavaliers

Cavaliers:

Sam Merrill: Questionable (Hip),

Darius Garland: Questionable (Toe),

Jarrett Allen: Questionable (Hand),

Max Strus: Out (Foot)

76ers

76ers:

Paul George: Day-To-Day (Knee),

Dominick Barlow: Day-To-Day (Elbow)

Cavaliers vs. 76ers Game Time and TV Channel

  • Game day: Wednesday, November 5, 2025
  • Game time: 7 p.m. ET
  • TV channel: FDSOH and NBCS-PH
  • Location: Cleveland, Ohio
  • Arena: Rocket Arena
  • Live stream: Watch this game on Fubo (Regional restrictions may apply)

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