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Big Ten opponents meet when the No. 23 USC Trojans (5-2) and the Nebraska Cornhuskers (6-2) play on Saturday, November 1, 2025 at Memorial Stadium (Lincoln, NE).
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USC vs. Nebraska Matchup Info
- Game date: Saturday, November 1, 2025
- Game time: 7:30 p.m. ET
- Location: Lincoln, Nebraska
- Venue: Memorial Stadium (Lincoln, NE)
- TV channel: NBC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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USC vs. Nebraska Odds and Prediction
- Spread favorite: Trojans (-4.5)
- Moneyline: Trojans (-195), Cornhuskers (+162)
- Total: 59 points
- Pick ATS: USC (-4.5)
- Pick OU: Over (59)
- Prediction: USC 32, Nebraska 27
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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USC vs. Nebraska Betting Records and Insights
- USC has covered four times in seven games with a spread this season.
- Nebraska has a record of just 2-5-1 against the spread this season.
- The Trojans have covered the spread twice when favored by 4.5 points or more this season (in five opportunities).
- USC games have gone over the point total four out of seven times this season.
- Nebraska games have hit the over six out of eight times this season.