Ole Miss vs. S. Carolina Football Prediction & Odds - Nov. 1

Ole Miss v Oklahoma

Photo: Brian Bahr / Getty Images Sport / Getty Images

The No. 7 Ole Miss Rebels (7-1) play a conference opponent when they host the South Carolina Gamecocks (3-5) on Saturday, November 1, 2025 at Vaught-Hemingway Stadium in an SEC battle.

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Ole Miss vs. South Carolina Matchup Info

  • Game date: Saturday, November 1, 2025
  • Game time: 7 p.m. ET
  • Location: Oxford, Mississippi
  • Venue: Vaught-Hemingway Stadium
  • TV channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Ole Miss vs. South Carolina Odds and Prediction

  • Spread favorite: Rebels (-12.5)
  • Moneyline: Rebels (-488), Gamecocks (+369)
  • Total: 55.5 points
  • Pick ATS: Ole Miss (-12.5)
  • Pick OU: Under (55.5)
  • Prediction: Ole Miss 34, South Carolina 16

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Ole Miss vs. South Carolina Betting Records and Insights

  • Ole Miss has compiled a 5-3-0 ATS record so far this year.
  • South Carolina has put together a 4-4-0 ATS record so far this year.
  • The Rebels have covered the spread twice this season (2-1 ATS) when playing as at least 12.5-point favorites.
  • In Ole Miss' eight games this season, the combined scoring has gone over the point total five times.
  • In South Carolina's eight contests this season, the combined scoring has gone over the point total three times.