UW vs. Illinois Football Prediction & Odds - Oct. 25

The Washington Huskies (5-2) host a Big Ten battle against the No. 23 Illinois Fighting Illini (5-2) on Saturday, October 25, 2025 at Alaska Airlines Field at Husky Stadium.

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Washington vs. Illinois Matchup Info

  • Game date: Saturday, October 25, 2025
  • Game time: 3:30 p.m. ET
  • Location: Seattle, Washington
  • Venue: Alaska Airlines Field at Husky Stadium
  • TV channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Washington vs. Illinois Odds and Prediction

  • Spread favorite: Huskies (-3.5)
  • Moneyline: Huskies (-163), Fighting Illini (+138)
  • Total: 54.5 points
  • Pick ATS: Illinois (+3.5)
  • Pick OU: Over (54.5)
  • Prediction: Illinois 30, Washington 26

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Washington vs. Illinois Betting Records and Insights

  • Washington has covered twice in six games with a spread this season.
  • Illinois has won five games against the spread this season, failing to cover twice.
  • The Huskies have been favored by 3.5 points or more four times this season, and covered the spread in two of those matchups.
  • The Fighting Illini have covered the spread once this year (1-2 ATS) when playing as at least 3.5-point underdogs.
  • Washington games have gone over the point total twice this season.
  • In Illinois' seven contests this season, the combined scoring has gone over the point total four times.