James Cook Week 8 Preview vs. the Panthers

James Cook has a tough matchup when his Buffalo Bills face the Carolina Panthers in Week 8 (Sunday, 1 p.m. ET). The Panthers give up 92.6 rushing yards per game, eighth-best in the league.

Cook has amassed a team-leading 537 yards on the ground after getting 107 attempts (89.5 ypg). He has scored five rushing TDs. Cook has also made a difference as a pass-catcher, catching 12 balls for 89 yards (14.8 ypg).

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Cook vs. the Panthers

• Cook vs the Panthers (since 2021): No games
• One opposing rusher has put up 100 or more rushing yards in a matchup against the Panthers during the 2025 season.
• Five opposing rushers have scored at least one touchdown on the ground against Carolina this year.
• The Panthers have not allowed any opposing players to record two or more rushing TDs against them this season.
• The Panthers give up 92.6 rushing yards per game, the NFL's eighth-ranked run defense this season.
• The Panthers have the No. 13 defense in the NFL in rushing touchdowns allowed, giving up five this season (0.7 per game).

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Cook Rushing Insights

• Cook has hit the over on his rushing yards totals in four games (66.7%) out of six opportunities.
• The Bills, who are 12th in NFL play in points scored, have passed 49.2% of the time while running 50.8%.
• He has handled 57.5% of his team's 186 rushing attempts this season (107).
• Cook has rushed for at least one touchdown four times this season, including one game with multiple rushing TDs.
• He has 25.0% of his team's 20 offensive touchdowns this season (five).
• He has 20 carries in the red zone (55.6% of his team's 36 red zone rushes).

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Cook's Recent Performance