Photo: Luke Hales / Getty Images Sport / Getty Images
Which team is going to win on Sunday, Oct. 26, when the Indianapolis Colts and Tennessee Titans match up at 4:25 p.m. ET? Our projection system believes in the Colts. Dive into our other projections below, where we break down the final score, spread, and over/under.
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Colts vs. Titans Game Info and TV Channel
- When: Sunday, October 26, 2025 at 4:25 p.m. ET
- Where: Lucas Oil Stadium in Indianapolis, Indiana
- TV: CBS
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Listen to the game on 107.5 The Fan
Colts vs. Titans Odds and Betting Info
- Spread favorite: Colts (-15)
- Moneyline: Colts (-1587), Titans (+874)
- Total: 47.5 points
Colts vs. Titans Prediction
- Pick ATS: Colts (-15)
- Pick OU: Under (47.5)
Prediction:
Colts 36 - Titans 11
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Colts vs. Titans Betting Insights
- The Colts have won five games against the spread this season, while failing to cover twice.
- The Titans have covered twice in seven chances against the spread this season.
- Indianapolis has covered the spread twice when favored by 15 points or more this season (in three opportunities).
- Tennessee has won its only game this year when playing as at least 15-point underdogs.
- So far this season, four out of the Colts' seven games have gone over the point total.
- The Titans and their opponent have combined to go over the point total four out of seven times this season.
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