SMU vs. Wake Forest Football Prediction & Odds - Oct. 25

The SMU Mustangs (5-2) square off against a conference opponent when they visit the Wake Forest Demon Deacons (4-2) on Saturday, October 25, 2025 at Allegacy Federal Credit Union Stadium in an ACC clash.

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SMU vs. Wake Forest Matchup Info

  • Game date: Saturday, October 25, 2025
  • Game time: 12 p.m. ET
  • Location: Winston-Salem, North Carolina
  • Venue: Allegacy Federal Credit Union Stadium
  • TV channel: The CW
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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SMU vs. Wake Forest Odds and Prediction

  • Spread favorite: Mustangs (-3.5)
  • Moneyline: Mustangs (-166), Demon Deacons (+140)
  • Total: 53.5 points
  • Pick ATS: Wake Forest (+3.5)
  • Pick OU: Under (53.5)
  • Prediction: Wake Forest 27, SMU 26

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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SMU vs. Wake Forest Betting Records and Insights

  • SMU has covered twice in six games with a spread this season.
  • Wake Forest has compiled a 4-2-0 record against the spread this season.
  • The Mustangs have covered the spread once this season (1-2 ATS) when playing as at least 3.5-point favorites.
  • The Demon Deacons have covered the spread twice this year (2-1 ATS) when playing as at least 3.5-point underdogs.
  • This season, games featuring the SMU have gone over the point total twice.
  • In Wake Forest's six contests this season, the combined scoring has gone over the point total four times.