Nebraska vs. Northwestern Football Prediction & Odds - Oct. 25

The Nebraska Cornhuskers (5-2) and the Northwestern Wildcats (5-2) play on Saturday, October 25, 2025 at Memorial Stadium (Lincoln, NE) in a clash of Big Ten foes.

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Nebraska vs. Northwestern Matchup Info

  • Game date: Saturday, October 25, 2025
  • Game time: 12 p.m. ET
  • Location: Lincoln, Nebraska
  • Venue: Memorial Stadium (Lincoln, NE)
  • TV channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Nebraska vs. Northwestern Odds and Prediction

  • Spread favorite: Cornhuskers (-7.5)
  • Moneyline: Cornhuskers (-292), Wildcats (+234)
  • Total: 44.5 points
  • Pick ATS: Northwestern (+7.5)
  • Pick OU: Over (44.5)
  • Prediction: Nebraska 24, Northwestern 21

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Nebraska vs. Northwestern Betting Records and Insights

  • Nebraska has won two games against the spread this season.
  • Northwestern is 5-2-0 ATS this year.
  • The Cornhuskers have been favored by 7.5 points or more three times this season, and covered the spread in two of those games.
  • The Wildcats have covered the spread when playing as at least 7.5-point underdogs in two of two opportunities this season.
  • Nebraska games have gone over the point total five out of seven times this season.
  • So far this year, two Northwestern games have gone over the point total.