Pistons vs. Bulls Predictions, Odds & Stats – Oct. 22

Detroit Pistons v Denver Nuggets

Photo: Matthew Stockman / Getty Images Sport / Getty Images

The Chicago Bulls are just 2.5-point underdogs against the Detroit Pistons in the season opener for both teams at United Center on Wednesday, October 22, 2025. The game starts at 8 p.m. ET on CHSN and FDSDET.

Watch the NBA, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up.

Pistons vs. Bulls Predictions for Wednesday

Our computer projection model for this encounter predicts a final result of Pistons 117, Bulls 116.

  • Moneyline Pick: Pistons (-141)
  • Total Pick: Under 236.5 (computer predicts 232.4 points)
  • Pick ATS: Bulls (+2.5)

Recent Pistons vs. Bulls Matchups

Pistons vs Bulls (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
2/12/2025 Pistons -6.5 237 -236 +195 128-110 DET
2/11/2025 Pistons -5 238.5 -199 +165 132-92 DET
2/2/2025 Pistons -5.5 233.5 -225 +188 127-119 DET
11/18/2024 Pistons -4 234 -180 +151 122-112 CHI

Pistons 2024-25 Betting Trends

  • Detroit was 43-39-0 against the spread last season.
  • The Pistons had an ATS record of 16-16 as 2.5-point favorites or more last year.
  • Of Detroit's 82 games last season, 42 hit the over.
  • The Pistons won 65% of the games last season in which they were favored on the moneyline (26-14).
  • In games it played as a moneyline favorite with odds of -141 or shorter last year, Detroit finished with a record of 22-10 (68.8%).

Bulls 2024-25 Betting Trends

  • Chicago covered 44 times in 82 games with a spread last season.
  • The Bulls had an ATS record of 29-24-1 as underdogs of 2.5 points or more last season.
  • A total of 44 of Chicago's games last year hit the over.
  • The Bulls were underdogs in 59 games last season and won 25 (42.4%) of those contests.
  • Chicago had a record of 19-32, a 37.3% win rate, when it was set as the underdog by +119 or more by oddsmakers last season.

Looking for NBA tickets? Head to StubHub today and see your team live.

Pistons vs. Bulls Injury Report

Pistons

Pistons:

Jaden Ivey: Out (Knee),

Marcus Sasser: Day-To-Day (Hip),

Caris LeVert: Probable (Knee)

Bulls

Bulls:

Zach Collins: Out (Wrist),

Coby White: Out (Calf)

Pistons vs. Bulls Game Time and TV Channel

  • Game day: Wednesday, October 22, 2025
  • Game time: 8 p.m. ET
  • TV channel: CHSN and FDSDET
  • Location: Chicago, Illinois
  • Arena: United Center
  • Live stream: Watch this game on Fubo (Regional restrictions may apply)

Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason.