
Big Ten opponents meet when the Iowa Hawkeyes (4-2) and the Penn State Nittany Lions (3-3) play on Saturday, October 18, 2025 at Kinnick Stadium.
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Iowa vs. Penn State Matchup Info
- Game date: Saturday, October 18, 2025
- Game time: 7 p.m. ET
- Location: Iowa City, Iowa
- Venue: Kinnick Stadium
- TV channel: Peacock
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Iowa vs. Penn State Odds and Prediction
- Spread favorite: Hawkeyes (-3)
- Moneyline: Hawkeyes (-157), Nittany Lions (+132)
- Total: 40.5 points
- Pick ATS: Iowa (-3)
- Pick OU: Over (40.5)
- Prediction: Iowa 34, Penn State 15
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Iowa vs. Penn State Betting Records and Insights
- Iowa has put together a 4-1-1 record against the spread this season.
- Penn State has not won against the spread this season in six opportunities.
- The Hawkeyes have covered the spread twice this season (2-1 ATS) when playing as at least 3-point favorites.
- This season, games featuring the Iowa have hit the over twice.
- So far this year, four of Penn State's six games with a set number have hit the over.