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The No. 2 Miami Hurricanes (5-0) host an ACC battle against the Louisville Cardinals (4-1) on Friday, October 17, 2025 at Hard Rock Stadium.
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Miami (FL) vs. Louisville Matchup Info
- Game date: Friday, October 17, 2025
- Game time: 7 p.m. ET
- Location: Miami Gardens, Florida
- Venue: Hard Rock Stadium
- TV channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Miami (FL) vs. Louisville Odds and Prediction
- Spread favorite: Hurricanes (-12.5)
- Moneyline: Hurricanes (-442), Cardinals (+343)
- Total: 49.5 points
- Pick ATS: Miami (FL) (-12.5)
- Pick OU: Over (49.5)
- Prediction: Miami (FL) 38, Louisville 13
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Miami (FL) vs. Louisville Betting Records and Insights
- Miami (FL) has put together a 4-1-0 ATS record so far this year.
- Louisville has a record of just 1-4-0 against the spread this year.
- The Hurricanes have covered the spread once this season (1-1 ATS) when playing as at least 12.5-point favorites.
- This season, games featuring the Miami (FL) have hit the over twice.
- Louisville games have hit the over three out of five times this season.