Arizona vs. Houston Football Prediction & Odds - Oct. 18

The Arizona Wildcats (4-2) hit the road for a Big 12 clash against the Houston Cougars (5-1) on Saturday, October 18, 2025 at TDECU Stadium.

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Arizona vs. Houston Matchup Info

  • Game date: Saturday, October 18, 2025
  • Game time: 12 p.m. ET
  • Location: Houston, Texas
  • Venue: TDECU Stadium
  • TV channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Arizona vs. Houston Odds and Prediction

  • Spread favorite: Wildcats (-1.5)
  • Moneyline: Wildcats (-114), Cougars (-105)
  • Total: 47.5 points
  • Pick ATS: Houston (+1.5)
  • Pick OU: Over (47.5)
  • Prediction: Houston 27, Arizona 23

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Arizona vs. Houston Betting Records and Insights

  • Arizona has compiled a 3-2-0 record against the spread this season.
  • Houston has put together a 4-2-0 record against the spread this year.
  • The Wildcats have won each of their two games this season when playing as at least 1.5-point favorites.
  • The Cougars have not covered the spread this year (0-1 ATS) when playing as at least 1.5-point underdogs.
  • So far this season, two Arizona games have hit the over.
  • In 2025, four Houston games have hit the over.