The Carolina Panthers should come out on top in their matchup against the Dallas Cowboys at 1 p.m. ET on Sunday, Oct. 12, based on our computer projections. If you're seeking additional predictions on the final score, spread, and point total, we list those numbers below.
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Cowboys vs. Panthers Game Info and TV Channel
- When: Sunday, October 12, 2025 at 1 p.m. ET
- Where: Bank of America Stadium in Charlotte, North Carolina
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 99.7 The Fox
Cowboys vs. Panthers Odds and Betting Info
- Spread favorite: Cowboys (-3)
- Moneyline: Cowboys (-170), Panthers (+141)
- Total: 49.5 points
Cowboys vs. Panthers Prediction
- Pick ATS: Panthers (+3)
- Pick OU: Over (49.5)
Prediction:
Panthers 29 - Cowboys 23
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Cowboys vs. Panthers Betting Insights
- The Cowboys are 3-2-0 ATS this season.
- The Panthers are 3-2-0 ATS this season.
- Dallas has not covered the spread when favored by 3 points or more this season (in one opportunity).
- Carolina has covered the spread twice as an underdog by 3 points or more this year (in four opportunities).
- In the Cowboys' five games this season, the combined scoring has gone over the point total three times.
- In 2025, three Panthers games have gone over the point total.
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