Photo: Ronald Martinez / Getty Images Sport / Getty Images
Matthew Stafford has a tough matchup when his Los Angeles Rams play the San Francisco 49ers in Week 5 (Thursday, 8:15 p.m. ET). The 49ers concede 165 passing yards per game, sixth-best in the NFL.
This season, Stafford has posted passing 1,114 yards (278.5 per game), going 92-for-136 (67.6%) through the air with eight touchdowns against two interceptions. In the ground game, Stafford has tacked on -4 yards rushing on 10 attempts.
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Stafford vs. the 49ers
- Stafford vs the 49ers (since 2021): 6 GP / 257.7 PASS YPG / 10 PASS TD
- No opposing quarterbacks have recorded 300 or more passing yards in an outing against San Francisco this season.
- Three players have tossed one or more TDs in a game against the 49ers this season.
- San Francisco has allowed one player to throw at least two touchdowns in a matchup in 2025.
- The 49ers have allowed at least three TD passes in an outing to one opposing QB this season.
- The 49ers give up 165 passing yards per game, the NFL's sixth-ranked pass defense this season.
- Opponents of the 49ers have scored five touchdowns through the air (1.3 per game). The 49ers' defense is seventh in the league in that category.
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Stafford Passing Insights
- Stafford has gone over his passing yards prop total in three of four opportunities this year.
- The Rams pass on 56.1% of their plays and run on 43.9%. They are 13th in NFL play in points scored.
- Stafford is No. 5 in the league averaging 8.2 yards per attempt (1,114 total yards passing).
- Stafford has thrown for a touchdown in all four games this season, with more than one TD pass three times.
- He has eight total touchdowns this season (72.7% of his team's 11 offensive TDs).
- Stafford has passed 20 times out of his 136 total attempts while in the red zone (51.3% of his team's red zone plays).
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Stafford's Recent Performance
| Opponent | Date | Week | Passing Stats | Rushing Stats |
|---|---|---|---|---|
| vs. Colts | 9/28/2025 | Week 4 | 29-for-41 / 375 YDS / 3 TDs / 0 INTs | 4 ATT / 4 YDS / 0 TDs |
| vs. Eagles | 9/21/2025 | Week 3 | 19-for-33 / 196 YDS / 2 TDs / 1 INT | 0 ATT / 0 YDS / 0 TDs |
| vs. Titans | 9/14/2025 | Week 2 | 23-for-33 / 298 YDS / 2 TDs / 1 INT | 2 ATT / -6 YDS / 0 TDs |
| vs. Texans | 9/7/2025 | Week 1 | 21-for-29 / 245 YDS / 1 TD / 0 INTs | 4 ATT / -2 YDS / 0 TDs |