Ohio St vs. UW Football Prediction & Odds - Sept. 27

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The No. 1 Ohio State Buckeyes (3-0) hit the road for a Big Ten clash against the Washington Huskies (3-0) on Saturday, September 27, 2025 at Alaska Airlines Field at Husky Stadium.

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Ohio State vs. Washington Matchup Info

  • Game date: Saturday, September 27, 2025
  • Game time: 3:30 p.m. ET
  • Location: Seattle, Washington
  • Venue: Alaska Airlines Field at Husky Stadium
  • TV channel: CBS
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Ohio State vs. Washington Odds and Prediction

  • Spread favorite: Buckeyes (-9)
  • Moneyline: Buckeyes (-327), Huskies (+261)
  • Total: 52.5 points
  • Pick ATS: Washington (+9)
  • Pick OU: Under (52.5)
  • Prediction: Washington 35, Ohio State 17

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Ohio State vs. Washington Betting Records and Insights

  • Ohio State has covered twice in three matchups with a spread this season.
  • Washington has a record of 1-1-0 against the spread this season.
  • The Buckeyes have been favored by 9 points or more two times this season, and covered the spread in one of those contests.
  • Games featuring Ohio State have gone over the point total once this season.
  • Washington games have gone over the point total twice this year.