Bills vs. Colts Week 10 Predictions, Odds and Stats

Miami Dolphins v Buffalo Bills

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In the contest between the Buffalo Bills and Indianapolis Colts on Sunday, Nov. 10 at 1 p.m. ET, our projection model expects the Bills to come away with the victory. Seeking predictions on the final score, spread, and point total, too? Find a complete game projection below.

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Bills vs. Colts Game Info and TV Channel

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Bills vs. Colts Odds and Betting Info

  • Spread favorite: Bills (-3.5)
  • Moneyline: Bills (-209), Colts (+174)
  • Total: 46.5 points

Bills vs. Colts Prediction

  • Pick ATS: Bills (-3.5)
  • Pick OU: Under (46.5)

Prediction:

Bills 26 - Colts 20

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Bills vs. Colts Betting Insights

    • The Bills are 5-4-0 ATS this season.
    • The Colts have compiled a 7-2-0 record against the spread this season.
    • Buffalo has covered the spread twice when favored by 3.5 points or more this season (in four opportunities).
    • Indianapolis has covered the spread twice as an underdog by 3.5 points or more this season (in three opportunities).
    • In the Bills' nine games this season, the combined scoring has gone over the point total five times.
    • In 2024, three Colts games have hit the over.

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