The College Football Playoff first round will see the Oregon Ducks (11-1) hosting the James Madison Dukes (12-1) at 7:30 p.m. ET at Autzen Stadium in Eugene, Oregon. Oregon is favored in the matchup, by 21.5 points.
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Oregon vs. James Madison Matchup Info
- Game date: Saturday, December 20, 2025
- Game time: 7:30 p.m. ET
- Location: Eugene, Oregon
- Venue: Autzen Stadium
- TV channel: TNT
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Oregon vs. James Madison Odds and Prediction
- Spread favorite: Ducks (-21.5)
- Moneyline: Ducks (-2083), Dukes (+1012)
- Total: 50.5 points
- Pick ATS: James Madison (+21.5)
- Pick OU: Over (50.5)
- Prediction: Oregon 33, James Madison 20
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Oregon vs. James Madison Betting Records and Insights
- Oregon is 7-5-0 ATS this season.
- James Madison is 8-5-0 ATS this season.
- The Ducks are 3-3 ATS this season when playing as at least 21.5-point favorites.
- Oregon games have gone over the point total six out of 12 times this season.
- In James Madison's 13 contests this season, the combined scoring has gone over the point total five times.