The Indiana Hoosiers (7-1) will host the Louisville Cardinals (7-1) after winning six home games in a row.
Saturday's game between the Cardinals and the Hoosiers features the Cardinals as 3.5-point favorites. A 160.5-point total is set for the game.
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Louisville vs. Indiana Odds and Game Info
- Game day: Saturday, December 6, 2025
- Game time: 2:15 p.m. ET
- TV channel: CBS
- Location: Indianapolis, Indiana
- Arena: Gainbridge Fieldhouse
- Live stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Louisville vs. Indiana Odds and Prediction
- Spread favorite: Louisville (-3.5)
- Moneyline: Louisville (-177), Indiana (+148)
- Total: 160.5 points
Pick ATS:Indiana (+3.5)
- Pick OU: Under (160.5)
- Prediction: Indiana 79, Louisville 77
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Louisville vs. Indiana Comparison
| Louisville Rank | Louisville Stat | Indiana Stat | Indiana Rank | |
|---|---|---|---|---|
| 7th | 94.6 | Points Scored | 86.4 | 57th |
| 49th | 66.3 | Points Allowed | 63.8 | 16th |
| 10th | 19.8 | Assists | 20.0 | 7th |
| 72nd | 10.3 | Turnovers | 8.9 | 16th |
| 106th | 47.2% | Field Goal % | 49.2% | 52nd |
| 8th | 36.9% | Field Goal % Allowed | 37.6% | 17th |
Louisville Key Players
- The scoring leader for the Cardinals this season is Ryan Conwell, who averages 19.5 points, 4.9 rebounds, and 2.6 assists per game.
- Sananda Fru is Louisville's leading rebounder, pulling down 6.1 per game, while Mikel Brown Jr. is its best passer, distributing 5.6 assists in each contest.
- Conwell leads the Cardinals in three-point shooting, making an average of 3.9 shots per game from beyond the arc.
- The Louisville steals leader is Kobe Rodgers, who averages 1.5 takeaways per game, while its blocks leader is Fru, who compiles 1.3 rejections per contest.
Indiana Key Players
- Tucker DeVries is the top scorer for the Hoosiers with 16.8 points per game. DeVries also tacks on 5.1 rebounds and 3.4 assists per game.
- Sam Alexis puts up a stat line of 6.0 rebounds, 10.5 points and 1.3 assists per game for Indiana to take the top rebound spot on the team. Tayton Conerway holds the top spot for assists with 4.9 per game, adding 12.6 points and 3.3 rebounds per contest.
- DeVries is consistent from three-point range and leads the Hoosiers with 3.6 made threes per game.
- Indiana's leader in steals is Conerway (2.1 per game), and its leader in blocks is Alexis (1.3 per game).
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