Penn State vs. Northwestern Football Prediction & Odds - Oct. 11

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Big Ten foes match up when the Penn State Nittany Lions (3-2) and the Northwestern Wildcats (3-2) square off on Saturday, October 11, 2025 at West Shore Home Field at Beaver Stadium.

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Penn State vs. Northwestern Matchup Info

  • Game date: Saturday, October 11, 2025
  • Game time: 3:30 p.m. ET
  • Location: University Park, Pennsylvania
  • Venue: West Shore Home Field at Beaver Stadium
  • TV channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Penn State vs. Northwestern Odds and Prediction

  • Spread favorite: Nittany Lions (-21.5)
  • Moneyline: Nittany Lions (-1695), Wildcats (+936)
  • Total: 47.5 points
  • Pick ATS: Northwestern (+21.5)
  • Pick OU: Under (47.5)
  • Prediction: Penn State 24, Northwestern 23

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Penn State vs. Northwestern Betting Records and Insights

  • Penn State is winless against the spread this season (0-5-0).
  • Northwestern has put together a 3-2-0 ATS record so far this year.
  • The Nittany Lions have not covered the spread when favored by 21.5 points or more this season (in four opportunities).
  • The Wildcats have won their only game this season when playing as at least 21.5-point underdogs.
  • A total of four out of five Penn State games this season have gone over the point total.
  • So far this season, two Northwestern games have hit the over.