The No. 11 LSU Tigers (4-1) square off against a fellow SEC foe when they host the South Carolina Gamecocks (3-2) on Saturday, October 11, 2025 at Tiger Stadium.
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LSU vs. South Carolina Matchup Info
- Game date: Saturday, October 11, 2025
- Game time: 7:45 p.m. ET
- Location: Baton Rouge, Louisiana
- Venue: Tiger Stadium
- TV channel: SEC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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LSU vs. South Carolina Odds and Prediction
- Spread favorite: Tigers (-8.5)
- Moneyline: Tigers (-336), Gamecocks (+267)
- Total: 44.5 points
- Pick ATS: LSU (-8.5)
- Pick OU: Under (44.5)
- Prediction: LSU 23, South Carolina 14
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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LSU vs. South Carolina Betting Records and Insights
- LSU has won two games against the spread this season.
- South Carolina has covered three times in five chances against the spread this year.
- The Tigers have not covered the spread this season (0-2 ATS) when playing as at least 8.5-point favorites.
- The Gamecocks have covered the spread when playing as at least 8.5-point underdogs in their only opportunity this season.
- So far this season, just one LSU game has gone over the point total.
- South Carolina games have hit the over twice this season.