The No. 1 Ohio State Buckeyes (5-0) hit the road for a Big Ten battle against the No. 17 Illinois Fighting Illini (5-1) on Saturday, October 11, 2025 at Memorial Stadium (Champaign, IL).
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Ohio State vs. Illinois Matchup Info
- Game date: Saturday, October 11, 2025
- Game time: 12 p.m. ET
- Location: Champaign, Illinois
- Venue: Memorial Stadium (Champaign, IL)
- TV channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Ohio State vs. Illinois Odds and Prediction
- Spread favorite: Buckeyes (-14.5)
- Moneyline: Buckeyes (-662), Fighting Illini (+482)
- Total: 50.5 points
- Pick ATS: Illinois (+14.5)
- Pick OU: Under (50.5)
- Prediction: Illinois 27, Ohio State 22
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Ohio State vs. Illinois Betting Records and Insights
- Ohio State has compiled a 4-1-0 ATS record so far this year.
- Illinois is 5-1-0 ATS this year.
- The Buckeyes have been favored by 14.5 points or more three times this season, and covered the spread in two of those contests.
- So far this season, two Ohio State games have gone over the point total.
- So far this season, four of Illinois' six games with a set number have hit the over.