Ohio St vs. Minnesota Football Prediction & Odds - Oct. 4

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The No. 1 Ohio State Buckeyes (4-0) take on a fellow Big Ten opponent when they host the Minnesota Golden Gophers (3-1) on Saturday, October 4, 2025 at Ohio Stadium.

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Ohio State vs. Minnesota Matchup Info

  • Game date: Saturday, October 4, 2025
  • Game time: 7:30 p.m. ET
  • Location: Columbus, Ohio
  • Venue: Ohio Stadium
  • TV channel: NBC
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Ohio State vs. Minnesota Odds and Prediction

  • Spread favorite: Buckeyes (-23.5)
  • Moneyline: Buckeyes (-3030), Golden Gophers (+1275)
  • Total: 43.5 points
  • Pick ATS: Ohio State (-23.5)
  • Pick OU: Under (43.5)
  • Prediction: Ohio State 32, Minnesota 6

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Ohio State vs. Minnesota Betting Records and Insights

  • Ohio State has compiled a 3-1-0 record against the spread this season.
  • Minnesota has won one game against the spread this year.
  • The Buckeyes have covered the spread once when favored by 23.5 points or more this season (in two opportunities).
  • Ohio State games have hit the over just once this season.
  • In 2025, three Minnesota games have gone over the point total.