Duke vs. Cal Football Prediction & Odds - Oct. 4

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The Duke Blue Devils (3-2) hit the road for an ACC showdown against the California Golden Bears (4-1) on Saturday, October 4, 2025 at California Memorial Stadium.

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Duke vs. Cal Matchup Info

  • Game date: Saturday, October 4, 2025
  • Game time: 10:30 p.m. ET
  • Location: Berkeley, California
  • Venue: California Memorial Stadium
  • TV channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Duke vs. Cal Odds and Prediction

  • Spread favorite: Blue Devils (-3)
  • Moneyline: Blue Devils (-162), Golden Bears (+136)
  • Total: 54.5 points
  • Pick ATS: Cal (+3)
  • Pick OU: Under (54.5)
  • Prediction: Duke 28, Cal 25

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Duke vs. Cal Betting Records and Insights

  • Duke has covered twice in five chances against the spread this season.
  • Cal has won three games against the spread this year, failing to cover twice.
  • The Blue Devils have been favored by 3 points or more three times this season, and covered the spread in two of those matchups.
  • The Golden Bears have covered the spread when playing as at least 3-point underdogs in their only opportunity this season.
  • So far this season, four of Duke's five games have gone over the point total.
  • Cal games have gone over the point total twice this year.

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