Trevor Lawrence Week 4 Preview vs. the 49ers

Jacksonville Jaguars quarterback Trevor Lawrence has a tough matchup in Week 4 (Sunday at 4:05 p.m. ET), playing the San Francisco 49ers. The 49ers are giving up the fifth-fewest passing yards in the NFL, 162 per game.

So far this year, Lawrence has put up passing 671 yards (223.7 per game), going 63-for-113 (55.8%) through the air with four touchdowns against four interceptions. Lawrence also has run the ball eight times for 25 yards, producing up 8.3 yards per game.

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Lawrence vs. the 49ers

• Lawrence vs the 49ers (since 2021): 1 GP / 158 PASS YPG / 0 PASS TD
• San Francisco has not allowed an opposing quarterback to register 300 or more passing yards in an outing this year.
• The 49ers have allowed two players to throw one or more TDs in a game this season.
• San Francisco has given up at least two passing touchdowns to one quarterback in 2025.
• The 49ers have allowed one opposing player to throw for at least three TD passes in an outing this season.
• The 49ers surrender 162 passing yards per game, the NFL's fifth-ranked pass defense this season.
• Opponents of the 49ers have put up four touchdowns through the air (1.3 per game). The 49ers' defense is 10th in the league in that category.

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Lawrence Passing Insights

• Lawrence has topped his passing yards prop total once in three chances.
• The Jaguars have passed 57.7% of the time and run 42.3% this season. They rank 15th in the NFL in scoring.
• Lawrence's 5.9 yards per attempt rank 25th in the NFL.
• Lawrence has completed at least one touchdown pass twice in three games, including multiple TDs once.
• He has 57.1% of his team's seven offensive touchdowns this season (four).
• Lawrence accounts for 48.5% of his team's red zone plays, with 16 of his total 113 passing attempts inside the opponent's 20-yard line.

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Lawrence's Recent Performance