SDSU vs. NIU Football Prediction & Odds - Sept. 27

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The San Diego State Aztecs (2-1) visit the Northern Illinois Huskies (1-2) at Brigham Field at Huskie Stadium on Saturday, September 27, 2025.

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San Diego State vs. Northern Illinois Matchup Info

  • Game date: Saturday, September 27, 2025
  • Game time: 3:30 p.m. ET
  • Location: DeKalb, Illinois
  • Venue: Brigham Field at Huskie Stadium
  • TV channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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San Diego State vs. Northern Illinois Odds and Prediction

  • Spread favorite: Aztecs (-2)
  • Moneyline: Aztecs (-128), Huskies (+108)
  • Total: 43 points
  • Pick ATS: Northern Illinois (+2)
  • Pick OU: Under (43)
  • Prediction: Northern Illinois 21, San Diego State 19

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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San Diego State vs. Northern Illinois Betting Records and Insights

  • San Diego State has won two games against the spread this season.
  • Northern Illinois has won one game against the spread this year.
  • The Aztecs have won their only game this season when playing as at least 2-point favorites.
  • The Huskies have been an underdog by 2 points or more two times this year, and covered the spread in one of those games.
  • Games featuring San Diego State have hit the over once this season.
  • Northern Illinois has yet to hit the over in any game this season.

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