
Big Ten opponents match up when the No. 19 Indiana Hoosiers (3-0) and the No. 9 Illinois Fighting Illini (3-0) play on Saturday, September 20, 2025 at Memorial Stadium (Bloomington, IN).
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Indiana vs. Illinois Matchup Info
- Game date: Saturday, September 20, 2025
- Game time: 7:30 p.m. ET
- Location: Bloomington, Indiana
- Venue: Memorial Stadium (Bloomington, IN)
- TV channel: NBC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Indiana vs. Illinois Odds and Prediction
- Spread favorite: Hoosiers (-7)
- Moneyline: Hoosiers (-260), Fighting Illini (+211)
- Total: 52.5 points
- Pick ATS: Indiana (-7)
- Pick OU: Under (52.5)
- Prediction: Indiana 31, Illinois 21
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Indiana vs. Illinois Betting Records and Insights
- Indiana has a record of 2-1-0 against the spread this season.
- Illinois has covered three times in three chances against the spread this year.
- The Hoosiers have been favored by 7 points or more three times this season, and covered the spread in two of those games.
- Indiana games have gone over the point total twice this season.
- Illinois games have gone over the point total once this season.