Our computer model predicts the Arizona Cardinals will beat the Carolina Panthers on Sunday, Sept. 14 at 4:05 p.m. ET. For a complete projection on the game at State Farm Stadium, which includes our prediction on the spread, over/under, and final score, keep scrolling.
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Cardinals vs. Panthers Game Info and TV Channel
- When: Sunday, September 14, 2025 at 4:05 p.m. ET
- Where: State Farm Stadium in Glendale, Arizona
- TV: CBS
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Listen to the game on 99.7 The Fox
Cardinals vs. Panthers Odds and Betting Info
- Spread favorite: Cardinals (-7)
- Moneyline: Cardinals (-326), Panthers (+260)
- Total: 44.5 points
Cardinals vs. Panthers Prediction
- Pick ATS: Cardinals (-7)
- Pick OU: Over (44.5)
Prediction:
Cardinals 34 - Panthers 15
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Cardinals vs. Panthers Betting Insights (2024 Stats)
- The Cardinals compiled an 11-6-0 record against the spread last season.
- The Panthers covered eight times in 17 chances against the spread last year.
- Carolina covered the spread four times last year (4-3 ATS) when playing as at least 7-point underdogs.
- Cardinals games hit the over eight out of 17 times last season.
- The Panthers and their opponent combined to hit the over 13 out of 17 times last season.
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