When the Arizona Cardinals play the New Orleans Saints at 1 p.m. ET on Sunday, Sept. 7, our projection system predicts the Cardinals will win the game. Our model also projects the spead, point total, and final score, which you can read below.
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Cardinals vs. Saints Game Info and TV Channel
- When: Sunday, September 7, 2025 at 1 p.m. ET
- Where: Caesars Superdome in New Orleans, Louisiana
- TV: CBS
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Cardinals vs. Saints Odds and Betting Info
- Spread favorite: Cardinals (-6.5)
- Moneyline: Cardinals (-287), Saints (+232)
- Total: 43.5 points
Cardinals vs. Saints Prediction
- Pick ATS: Cardinals (-6.5)
- Pick OU: Over (43.5)
Prediction:
Cardinals 26 - Saints 19
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Cardinals vs. Saints Betting Insights (2024 Stats)
- The Cardinals won 11 games against the spread last season, failing to cover six times.
- The Saints won seven games against the spread last year, while failing to cover 10 times.
- New Orleans covered the spread three times last season (3-2 ATS) when playing as at least 6.5-point underdogs.
- The Cardinals and their opponents combined to hit the over eight out of 17 times last season.
- Saints games went over the point total eight out of 17 times last year.
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