The No. 11 Illinois Fighting Illini (1-0) hit the road to take on the Duke Blue Devils (1-0) at Brooks Field at Wallace Wade Stadium on Saturday, September 6, 2025.
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Illinois vs. Duke Matchup Info
- Game date: Saturday, September 6, 2025
- Game time: 12 p.m. ET
- Location: Wilmington, North Carolina
- Venue: Brooks Field at Wallace Wade Stadium
- TV channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Illinois vs. Duke Odds and Prediction
- Spread favorite: Fighting Illini (-2.5)
- Moneyline: Fighting Illini (-137), Blue Devils (+115)
- Total: 49.5 points
- Pick ATS: Illinois (-2.5)
- Pick OU: Over (49.5)
- Prediction: Illinois 28, Duke 23
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Illinois vs. Duke Betting Records and Insights
- Illinois has covered in its only game with a spread this season.
- Duke is winless against the spread this season (0-1-0).
- The Fighting Illini have been favored by 2.5 points or more once this season, and covered the spread.
- So far this season, one Duke game has gone over the point total.