Duke vs Louisville Predictions - ACC Tournament

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The No. 1 seed Duke Blue Devils (30-3, 19-1 ACC) will look to claim the ACC championship and a guaranteed spot in the NCAA Tournament when they meet the No. 2 Louisville Cardinals (27-6, 18-2 ACC) on Saturday at 8:30 p.m. ET.

Saturday's game between the Blue Devils and the Cardinals sees the Blue Devils as a solid, 6.5-point favorite. The point total for the game is 147.5.

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Duke vs. Louisville Odds and Game Info

  • Game day: Saturday, March 15, 2025
  • Game time: 8:30 p.m. ET
  • TV channel: ESPN
  • Location: Charlotte, North Carolina
  • Arena: Spectrum Center

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Duke vs. Louisville Odds and Prediction

  • Spread favorite: Duke (-6.5)
  • Moneyline: Duke (-275), Louisville (+220)
  • Total: 147.5 points

Pick ATS:Duke (-6.5)

  • Pick OU: Under (147.5)
  • Prediction: Duke 78, Louisville 69

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Duke vs. Louisville Comparison

Duke Rank Duke Stat Louisville Stat Louisville Rank
14th 83.0 Points Scored 79.1 55th
7th 61.9 Points Allowed 68.8 79th
15th 16.9 Assists 14.1 136th
15th 9.2 Turnovers 11.0 162nd
16th 48.9% Field Goal % 45.6% 128th
7th 38.7% Field Goal % Allowed 42.4% 93rd

Duke Key Players

  • The Blue Devils leader in points, rebounds and assists is Cooper Flagg, who averages 18.9 points, 7.5 boards and 4.1 assists per game.
  • Kon Knueppel leads the Blue Devils in three-point shooting, making an average of 2.2 shots per game from beyond the arc.
  • Flagg is Duke's leader in steals and blocks, racking up 1.5 steals and 1.2 blocks per game.

Louisville Key Players

  • The Cardinals' Chucky Hepburn puts up enough points (16.3 per game) and assists (5.9 per game) to top the team's leaderboards.
  • J'Vonne Hadley's stat line of 7.4 rebounds, 12.3 points and 1.9 assists per game secures the top spot on the Louisville rebounding leaderboard.
  • Reyne Smith is the most prolific from deep for the Cardinals, hitting 3.5 threes per game.
  • Hepburn (2.5 steals per game) is the steal leader for Louisville while James Scott (0.8 blocks per game) is the block leader.

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