Colts vs. Titans Week 16 Predictions, Odds and Stats

Indianapolis Colts v Denver Broncos

Photo: Getty Images

Which team is going to come out on top on Sunday, Dec. 22, when the Indianapolis Colts and Tennessee Titans go head to head at 1 p.m. ET? Our projection model sides with the Colts. Check out our other predictions below, where we break down the final score, spread, and over/under.

Don't miss a touchdown this NFL season. Catch every score with NFL RedZone on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Sign up today and watch seven hours of commercial-free football from every NFL game every Sunday.

Colts vs. Titans Game Info and TV Channel

Catch every NFL touchdown with NFL RedZone on Fubo.

Colts vs. Titans Odds and Betting Info

  • Spread favorite: Colts (-3.5)
  • Moneyline: Colts (-194), Titans (+161)
  • Total: 42.5 points

Colts vs. Titans Prediction

  • Pick ATS: Colts (-3.5)
  • Pick OU: Over (42.5)

Prediction:

Colts 28 - Titans 17

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

    See how these predictions pan out and sign up for NFL RedZone on Fubo to catch every score on Sundays this fall.

    Colts vs. Titans Betting Insights

    • The Colts are 8-6-0 ATS this season.
    • The Titans have covered just twice in 14 matchups with a spread this season.
    • Tennessee has been an underdog by 3.5 points or more nine times this year, and covered the spread in one of those matchups.
    • The Colts and their opponent have combined to hit the over seven out of 14 times this season.
    • In the Titans' 14 contests this year, the combined scoring has gone over the point total eight times.

    Looking for NFL tickets? Head to StubHub today and see your team live.