Clemson vs. Louisville Football Prediction & Odds - Nov. 2

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The No. 11 Clemson Tigers (6-1) square off against a fellow ACC opponent when they host the Louisville Cardinals (5-3) on Saturday, November 2, 2024 at Memorial Stadium (Clemson, SC).

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Clemson vs. Louisville Matchup Info

  • Game date: Saturday, November 2, 2024
  • Game time: 7:30 p.m. ET
  • Location: Berkeley, California
  • Venue: Memorial Stadium (Clemson, SC)
  • TV channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Clemson vs. Louisville Odds and Prediction

  • Spread favorite: Tigers (-10.5)
  • Moneyline: Tigers (-380), Cardinals (+294)
  • Total: 62 points

Pick ATS:Louisville (+10.5)

  • Pick OU: Over (62)
  • Prediction: Clemson 34, Louisville 29

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Clemson vs. Louisville Betting Records and Insights

  • Clemson is 4-3-0 ATS this season.
  • Louisville has covered twice in seven matchups with a spread this season.
  • The Tigers have been favored by 10.5 points or more six times this season, and covered the spread in four of those matchups.
  • Clemson and its opponent have combined to hit the over three out of seven times this season.
  • In Louisville's seven contests this season, the combined scoring has gone over the point total five times.